C10 Impact of insulin resistance on ventricular relaxation in uncomplicated hypertension
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Abdominal obesity, insulin resistance and hypertension: impact on left ventricular mass and function in women.
OBJECTIVE To evaluate the relationship between central obesity, hyperinsulinemia and arterial hypertension with left ventricular mass and geometry in women. METHODS This study included 70 women (35-68 years), divided into four groups according to the presence of central obesity and hypertension. Visceral fat area was determined. Blood glucose and plasma insulin were determined before and two ...
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15 صفحه اولInsulin Resistance and Hypertension
Insulin resistance refers to the reduction in insulinmediated glucose uptake in insulin-sensitive tissues, specifically in skeletal muscle. As a compensatory response, hyperinsulinemia ensues to maintain normal blood glucose levels. In epidemiological studies, fasting insulin level is commonly used as a surrogate marker of insulin resistance. In normoglycemic subjects, fasting insulin correlate...
متن کاملInsulin resistance and hypertension.
A common mechanism which may be involved in the development of hypertension in both type I and type II diabetes mellitus is a deficiency of insulin at the cellular level. Observations from a number of laboratories suggest that impaired cellular response to insulin rather than hyperinsulinemia predisposes to increased vascular smooth muscle tone (the hallmark of hypertension in the diabetic stat...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 1997
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(97)89270-9